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Disclosure of interest: All authors: nothing to disclose E-Posters - DIGITAL TRANSFORMATION, AI AND ROBOTICS 07.00 - DIGITAL TRANSFORMATION, AI AND ROBOTICS - 07.01 - TECHNOLOGY INNOVATIONS: ROBOTS, VIRTUAL REALITY, ARTIFICIAL INTELLIGENCE AND MORE P2597 - ESOC25-1291 COMPUTATIONAL MODELLING OF LARGE VESSEL OCCLUSION THROMBOLYSIS IN THE CIRCLE OF WILLIS Yilin Yang 1 , Boram Gu 2 , Yun Xu 1 1 Imperial college london, london, United Kingdom, 2 Chonnam National University, Gwangju, South Korea Background and Aims: Early recanalization in bridging thrombolysis for large-vessel occlusion (LVO) stroke associated with favorable clinical outcomes