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The inhibition of NF-κB p65 nuclear translocation by sulforaphane in human retinal pigment epithelial (ARPE-19) cells exposed to blue light is coupled with the Nrf2 pathway, which, in turn, is associated with increased protein expression of SIRT1 and PGC-1α gene expression [134]

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The diffuse nature of autoimmune thyroiditis, the characteristic hypothyroidism and involvement of the pyramidal lobe are usually sufficient for differentiation