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This pattern has also been observed in experimental studies with 3.5- to 4.5-week-old rats (human adolescent), which demonstrated age differences in CBF response to weight drop injury, with young adult animals showing a greater reduction in blood flow at the injury site 2 hours post injury (Grundl et al., 1994)

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The capsids then acquire their final envelope from a cellular compartment before reaching the cell surface 37,38