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Figure 7 Dihexa does not protect hair cells from cisplatin Previous work with chemical and genetic cell death modulators suggests that cisplatin and aminoglycosides share some cell death pathways while also activating a distinct subset of signaling pathways (Owens et al., 8)

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However, some research centers adjust dosing based on body weight using 0.1-0.15 mg/kg daily, resulting in 7-10.5 mg daily for a 70 kg individual [4]