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Moreover, vitamin D deficiency has been identified as a potential risk factor for the development of hypothyroidism and thyroid autoimmunity (Tang et al., 2023
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While no further (pre)clinical interventions with NAD + modulators have been reported for this condition 263,264 , a Singaporean cohort study showed lower concentrations of circulating trigonelline, the N-methylated form of NA, in sarcopenic subjects 124
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