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Similarly, resistance to oxidative attack increased after overexpression of GPX5 in CHO-K1 cells, and GPX5 overexpressing cells reduced lipid peroxidation levels and downstream DNA damage marker 8-OXODG levels compared to control cells (Taylor et al., 2013)

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We tested for dose response by pathological stage of diagnosis and tumor grades among cases using multiple linear regression models, whereby continuous measures of carnitine (per 1-SD increase) were the independent variables, and pathological stages of diagnosis and tumor grades were dependent variables