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Rubinstein-Taybi syndrome: An immune deficiency as a cause for recurrent infections

clinically-tested

mg:10mg

Small molecule NNMT inhibitors have been developed and tested in animals, including tricyclic compounds aimed at metabolic disease (the Scientific Reports paper describing novel tricyclic small molecule inhibitors of nicotinamide N-methyltransferase for metabolic disease), and NNMT inhibition has been combined with calorie restriction in diet induced obese mice (the study of a reduced calorie diet combined with NNMT inhibition establishing a distinct microbiome in diet induced obese mice)