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Increasing type-IV collagen-mediated signaling drastically increases metastases in multiple tumor types, especially those with markedly higher IGF1R expression levels (Lalonde et al., 2014)

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Caspase-3 activity in HepG2 cells treated with aspirin and after manipulation of GSH levels by BSO and NAC was measured using DEVD peptide conjugated to p-nitroanaline as described in the vendor's protocol (Figures 8A, B)