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Duotone aurora — cool blue brief on the left, soft violet sheet on the right for cargo details.
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SASP factors are secreted through both paracrine and autocrine, inducing the NF-κB pathway, inducing senescence in neighboring cells and promoting inflammation
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Systemic administration (injectable or oral), which is less common than topical use and not part of approved or standard applications, would theoretically carry different safety considerations requiring appropriate clinical evaluation, though limited research on parenteral administration in animals has suggested acceptable safety profiles at moderate doses