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Duotone aurora — cool blue brief on the left, soft violet sheet on the right for cargo details.
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Oncogenic PIK3CA increases the dependency of cancer cells on glutamine by upregulating the expression of mitochondrial GPT2, which catalyzes the transamination reaction that converts glutamate and pyruvate into α-KG and alanine 175
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Together, maintaining the B12 biosynthesis in enteric pathogens provides a metabolic advantage to outcompete their intestinal microbiota counterparts in an inflamed gut
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