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Conversely, certain Clostridium species (phylum Firmicutes) are enriched in melanoma and colorectal cancer, where they promote tumour progression by activating the Wnt pathway and suppressing immune responses

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Animal studies have shown that FMT can upregulate brain-derived neurotrophic factor (BDNF) in the hippocampus, leading to improvements in social behavior in ASD models (D’Amato et al., 2020