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For example, a 19-year-old woman had been diagnosed with glutathione synthetase deficiency shortly after birth and then, despite an initial severe presentation, had normal intellectual development and few disease-related complications with a treatment regimen that included Polycitra (citric acid, potassium citrate, and sodium citrate), vitamin C, vitamin E, and selenium (08)
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Reactivity, in biological systems, is almost inevitably associated with toxicity, and ROS can damage various biological molecules: lipids (causing lipid peroxidation and membrane damage), DNA (causing DNA breaks), and proteins (causing, for instance, oxidation of various amino acids and inactivation of essential enzymes)
