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Influx CMTs The SLC transporters involved in influx at the BBB may be divided into different groups, as follows: simple (a) Hexose transport system for glucose and mannose such as glucose transporters (i.e., Glut-1 and Glut-3) 50,51 (b)Monocarboxylic acid transport (MCT) system such as MCT1 and MCT 8 for transportation of lactate, short-chain fatty acids, biotin, salicylic acid, valproic acid, phenylbutyrate and 3,5,3β-triiodo-L-thyronine 52-56 (c) Neutral amino acids transporter (NAAT), system L, divided into large (LAT1) and small (LAT2) neutral amino acid transporter systems for transportation of neutral amino acids and some drugs such as L-dopa 57-59 (d) Anionic amino acids transporters for transportation of aspartate and glutamate 60-62 (e)Cationic amino acids transporter, system y + , for transportation of L-lysine, L-arginine, and L-ornithine 63,64 (f)Beta amino acid transporter for transportation of Ξ²-alanine and taurine 65-67 (g)Choline transport system for transportation of choline and thiamine through organic cation transporter (OCT) family 68-70 (h)Nucleoside transport system 71 (i)Peptide transporters, including oligopeptide transporters (e.g., PepT1, PepT2) and polypeptide transport system (e.g., Oatp2, OAT-K1, OATP)72, 73 (j)Medium-chain fatty acid transporter
