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Recently a 2020 FDA Drug Safety Communication plainly states “ there were variations in the duration of the withdrawal symptoms that lasted from weeks to years.” Anecdotally, many patients afflicted with protracted withdrawal from benzodiazepines post-cessation disclose that when they report to their medical provider complaining of the symptoms and the duration they are met with disbelief

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One cluster analysis of 131 ME/CFS patients diagnosed according to the Fukuda criteria revealed that 34% of patients experienced sympathetic symptoms with dysautonomia (and were associated with more severe disease severity), 5% from sympathetic symptoms alone, 21% parasympathetic, and 40% struggled with sympathovagal balance (331)